Polynucleotides in Cambridge

Polynucleotides are regenerative injectable treatments based on purified DNA fragments. Rather than adding volume or hydration directly, they support the skin’s own repair processes — improving elasticity, texture and resilience over time. They are commonly used for the under-eye area and for overall skin quality.

Highly purified DNA fragments, most commonly derived from salmon or trout and selected for biocompatibility. Suitability — including any relevant allergies — is checked at your consultation.

Often, yes — this is one of their most frequently requested uses. The under-eye skin is usually too delicate for filler, and polynucleotides aim to improve skin thickness, tone and the appearance of dark circles regeneratively. Suitability depends on the cause of your concern, which we assess first.

Profhilo hydrates and firms using hyaluronic acid; polynucleotides work on repair and regeneration at a cellular level. They are complementary, and some treatment plans combine them. Which is recommended depends on your skin and goals.

Standard skin boosters place hyaluronic acid into the skin mainly to improve hydration and glow. Polynucleotides do not add hydration directly; they support the skin’s repair biology to improve structure and elasticity over time, which makes them a common choice for the under-eye area and crepey skin.

A course is commonly recommended, but the number and spacing of sessions depend on the product used, the treatment area and your individual plan. Your practitioner will confirm a realistic course and timeline at your consultation.

Some clients notice fresher-looking skin after the first session, but because polynucleotides work through the skin’s own repair processes, the main improvements in texture, firmness and the under-eye area build gradually over the course and in the weeks following the final session.

This varies with the product, the area treated, your skin and lifestyle factors such as sun exposure and smoking. Many clients maintain results with a single session every six to twelve months, agreed at your review.

Very little. Small bumps at the injection points usually settle within 24–48 hours and mild bruising is possible, particularly under the eyes. Most clients return to normal activities the same or next day, avoiding makeup on the area for 12–24 hours and heat, alcohol and strenuous exercise for 24 hours.

Guide prices at NexGen Clinic start from £180 per session. The cost of a course depends on the product, the area treated and the number of sessions recommended for you, and is confirmed in writing at your free consultation before anything is booked. Our full pricelist can be downloaded from this page.

You do not need to decide in advance. At your consultation we assess the area, discuss your goals and medical history and recommend the approach most likely to achieve a natural result — which may be polynucleotides, Profhilo, a skin booster, a combination or something else entirely.